February 18, 2014

TD5 Lab

Fernando Danilo González-Nilo

Full Professor and Director of the                                                              
Center for Bioinformatics and Integrative Biology (CBIB)  
+56-2-770 3405

Dr. Fernando Danilo González Nilo, Ph.D. in Chemistry (47), is a full professor and Director of the Center for Bioinformatics and Integrative Biology (CBIB), at Universidad Andres Bello. The CBIB of the University Andres Bello houses a trans-disciplinary team whose main goal is to develop research strategies that bring together the benefits of computational and experimental validation methods. The CBIB highly integrated approach favors an iterative research cycle based on observation, modeling, simulation, and validation. This approach is supported by a high performance computing system (SGI ICE 8400 with 1.536 cores and 3TB of RAM memory), enabling the development and use of high-performance molecular simulation and bioinformatics tools in areas as diverse as Molecular Design, Protein Engineering, and Omics-Technologies. The computer system is tightly integrated to the Protein Engineering, Cell biology and Electron Microscopy laboratories. This arrangement in central to CBIB design for the development of multidisciplinary initiatives that allow exploring new questions in integrative biology.

CBIB team take part in multiple theoretical-experimental projects through collaborative efforts with national and international groups specialized in biophysics, enzymatic catalysis, computer based drug design, transmembrane proteins and bio- and nano-technology, among others. Other line of focus within the CBIB, is the development and implementation of advanced methods in Molecular Dynamics simulations for the analysis and characterization of the structural determinants that govern the activation and conductance of K channels (SHAKER, HSlo, TRPV1 and TRPM8).