April 22, 2015

Biosystems Engineering Lab

Ignacio Poblete-Castro

Assistant Professor   
ignacio.poblete@unab.cl
+56-2-2770 3625

 Our group focuses on engineering biological systems for the synthesis of value-added chemical compounds. Among them, we center our attention to the production of biodegradable polymers, biofuels, proteins, and organic acids. Driven by a systems biotechnological approach we also pursue to develop new bioprocesses using waste materials as carbon substrates, where the host strain is modulated (rewire) and coupled to the process to improve performance in bioreactors. In addition, we also attempt to systematically understand microbial metabolism (single and communities) via metabolic network reconstruction and simulation. 

Publications

2018


 TITLEAUTHORSJOURNAL
12Genome sequence of two members of the chloroaromatic-degrading MT community: Pseudomonas reinekei MT1 and Achromobacter xylosoxidans MT3.Gutierrez-Urrutia I,  Miossec MJ , Valenzuela SL, Meneses C, Dos Santos VAPM,  Castro-Nallar E, Poblete-Castro I.Journal of Biotechnology. 2018. DOI: 10.1016/j.jbiotec.2018.03.019.

2017


 TITLEAUTHORSJOURNAL
107Co-synthesis of medium-chain-length polyhydroxyalkanoates and CdS quantum dots nanoparticles in Pseudomonas putida KT2440.Oliva-Arancibia B, Órdenes-Aenishanslins N,  Bruna N , Ibarra PS, Zacconi FC,  Pérez-Donoso JM, Poblete-Castro I. Journal of Biotechnology. 2017. DOI: 10.1016/j.jbiotec.2017.10.013
101A novel programmable lysozyme-based lysis system in Pseudomonas putida for biopolymer production.Borrero-de Acuña JM, Hidalgo-Dumont,Pacheco N, Cabrera A,  Poblete-Castro I. Scientific Reports. 2017 DOI: 10.1038/s41598-017-04741-2.
74Multi-level evaluation of Escherichia coli polyphosphate related mutants using global transcriptomic, proteomic and phenomic analyses.Varas M, Valdivieso C, Mauriaca C, Ortíz-Severín J, Paradela A,  Poblete-Castro I , Cabrera R, Chávez FP.Biochemica et Biophysica acta. 2017. DOI: 10.1016/j.bbagen.2017.01.007
73Datasets for transcriptomics, q-proteomics and phenotype microarrays of polyphosphate metabolism mutants from Escherichia coli.Macarena Varas, Camilo Valdivieso, Cecilia Mauriaca,a Javiera Ortíz-Severín, Alberto Paradela,  Ignacio Poblete-Castro , Ricardo Cabrera, Francisco P. Cháveza.Data Brief. 2017. DOI: 10.1016/j.dib.2017.03.010
72Batch Cultivation Model for Biopolymer Production.C. E. Torres-Cerna, A. Y. Alanis,a, I. Poblete-Castro , E. A. Hernandez-Vargas.Chemical and Biochemical Engineering Quarterly. 2017. DOI: 10.15255/CABEQ.2016.952

2016


 TITLEAUTHORSJOURNAL
53Integrated analysis of gene expression and metabolic fluxes in PHA-producing Pseudomonas putida grown on glycerolBeckers, V.; Poblete-Castro, I.; Tomasch, J.; Wittmann, C.Microbial Cell Factories. 2016, DOI: 10.1186/s12934-016-0470-2

2015


 TITLEAUTHORSJOURNAL
15Draft Genome Sequence of the Phenol-Degrading Bacterium Pseudomonas putida H.Vizoso P, Pacheco N, Bastias-Molina M, Meneses C, Poblete-Castro I.Genome Announcement. 2015. DOI: 10.1128/genomeA.00936-15.

2014


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2013


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2012


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